Roth collaborates on major new interactome map

Frederick (Fritz) Roth, Canada Excellence Research Chair in Integrative Biology at the University of Toronto, co-led the development of a new map that describes the complex network of interactions between human proteins.

Published in Cell, the systemic map of some 14,000 high-quality, human binary protein-protein interactions provides proteome-wide coverage of the human interactome network (an interactome is the whole set of molecular interactions in a given cell).

The groundbreaking map shows that there is significant interconnectivity between known and candidate cancer gene products, and provides unbiased evidence for researchers to use in developing an expanded functional human disease landscape.

Read the article here.